In vitro antimycobacterial activities of capuramycin analogues.
نویسندگان
چکیده
Translocase I inhibitor compounds derived from capuramycin demonstrated rapid bactericidal activity against several different mycobacterial species. SQ641 was the most active of the compounds, with a MIC of 0.12 to 8 microg/ml, a postantibiotic effect of 55 h, and interesting synergistic effects with other antitubercular drugs.
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 52 2 شماره
صفحات -
تاریخ انتشار 2008